P103 QUANTITATIVE EXPRESSION OF CD64 ON POLYMORPHONUCLEAR NEUTROPHILS: A NEW DIAGNOSTIC TOOL IN IBD
نویسندگان
چکیده
منابع مشابه
Evaluation of CD64 Expression on Peripheral Blood Neutrophils for Early Detection of Neonatal Sepsis
Background: Neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. The clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. Objective: The aim of this study was to determine the importance of CD64 expression (FcgRI), a neutrophil surface marker, in ea...
متن کاملAnalysis of Autofluorescence in Polymorphonuclear Neutrophils: A New Tool for Early Infection Diagnosis
Diagnosing bacterial infection (BI) remains a challenge for the attending physician. An ex vivo infection model based on human fixed polymorphonuclear neutrophils (PMNs) gives an autofluorescence signal that differs significantly between stimulated and unstimulated cells. We took advantage of this property for use in an in vivo pneumonia mouse model and in patients hospitalized with bacterial p...
متن کاملevaluation of cd64 expression on peripheral blood neutrophils for early detection of neonatal sepsis
background: neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. the clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. objective: the aim of this study was to determine the importance of cd64 expression (fcgri), a neutrophil surface marker, in ea...
متن کاملExpression of CD64 on Circulating Neutrophils Favoring Systemic Inflammatory Status in Erythema Nodosum Leprosum
Erythema Nodosum Leprosum (ENL) is an immune reaction in leprosy that aggravates the patient´s clinical condition. ENL presents systemic symptoms of an acute infectious syndrome with high leukocytosis and intense malaise clinically similar to sepsis. The treatment of ENL patients requires immunosuppression and thus needs to be early and efficient to prevent both disabilities and permanent nerve...
متن کاملUpregulation of major histocompatibility complex class II, CD83, CD64, and CD14 on polymorphonuclear neutrophils stimulated with interleukin-15.
BACKGROUND AND PURPOSE Polymorphonuclear neutrophils (PMNs) act as a first line of defense against bacterial infections. Recent studies indicated that PMNs could act as antigen-presenting cells. The aim of this study was to detect the expression of major histocompatibility complex (MHC) class II and certain molecules and receptors (CD83, CD64, and CD14) on the surface of PMNs stimulated with in...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis Supplements
سال: 2007
ISSN: 1873-9954
DOI: 10.1016/s1873-9954(07)70115-5